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Study identifier: NCT05303805 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Topical Sevoflurane for Treatment of Chronic Leg Ulcers

Condition: Leg Ulcer  ·  Sponsor: Charles University, Czech Republic

PhasePhase 4
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Patients with painful non-healing leg ulcer will be enrolled in the clinical single-blinded randomized study. The active treatment group will have sevoflurane applied at approximately 1 ml/cm2 at the start of wound treatment, the control group will only have a standard rinse solution with Cyteal TM (Pierre Fabre Medicament, France). Further treatment will then be carried out in the standard manner. The duration of the study will be 5 days; if the defect heals earlier, it will be terminated early. Exclusion criteria: allergy to sevoflurane, inability to understand the questionnaire Parameters to be monitored will be pain intensity, microbial colonization, appearance and size of the defect

This description comes directly from the study's public registry record.

Talk to the study team

Jiri Malek, M.D.  ·  +4202671622461  ·  malekj@fnkv.cz

Jiri Malek, M.D.  ·  +4202671622272461  ·  malekj@fnkv.cz

Always discuss trial participation with your own doctor first.

Locations (1)

Faculty Hospital Kralovske VinohradyPrague, CzechiaRecruiting

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Source record: clinicaltrials.gov/study/NCT05303805