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Study identifier: NCT05301881 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

COntinue the SaMe Systemic Therapy After Local Ablative Therapy for Oligo Progression in Metastatic Breast Cancer - the COSMO Study

Condition: Breast Cancer Invasive · Metastatic Cancer · Oligoprogressive  ·  Sponsor: The Netherlands Cancer Institute

PhasePhase 2
Planned participants118
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Patients with oligoprogression of metastatic breast cancer during palliative treatment that is amenable to local therapy will be included. The local ablative therapy (LAT) may consist of stereotactic ablative radiotherapy (SABR), also known as stereotactic body radiation therapy, surgery or radiofrequency ablation (RFA).

This description comes directly from the study's public registry record.

Talk to the study team

G Sonke, MD  ·  +31-20-512  ·  g.sonke@nki.nl

A Almekinders  ·  c.almekinders@nki.nl

Always discuss trial participation with your own doctor first.

Locations (7)

Noordwest ZiekenhuisgroepAlkmaar, NetherlandsNot Yet Recruiting
Antoni van LeeuwenhoekAmsterdam, NetherlandsRecruiting
RijnstateArnhem, NetherlandsRecruiting
Deventer ziekenhuisDeventer, NetherlandsNot Yet Recruiting
ADRZGoes, NetherlandsRecruiting
Martini ziekenhuisGroningen, NetherlandsNot Yet Recruiting
Antonius ziekenhuisUtrecht, NetherlandsNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05301881