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Study identifier: NCT05301413 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Social Determinants and a Diabetes Prevention Program Tailored for African Americans

Condition: PreDiabetes · Overweight and Obesity  ·  Sponsor: University of Missouri, Kansas City

PhasePhase 2
Planned participants360
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

African Americans (AAs) have rates of diabetes mellitus (DM) twice that of Whites and are disproportionately affected by leading risk factors for DM - obesity and low-income. A critical strategy in the battle against DM is the Diabetes Prevention Program (DPP), an evidence-based intervention that significantly delays or prevents Type 2 diabetes through the promotion of diet change, exercise and modest weight loss. However, weight loss from the DPP among AAs is about half that of White participants, and suboptimal AA attendance is a critical contributor. The investigators propose to conduct a study that will address social determinants (SD) that challenge DPP attendance with underserved African Americans from a safety net hospital. The investigators will examine DPP attendance and weight loss with participants randomized to 3 groups: standard DPP, a culturally-tailored DPP to address acceptability, and a culturally-tailored DPP enhanced to address socioeconomic-related barriers to DPP participation. This novel study is the first to tailor the DPP to address SD cultural and socioeconomic barriers that limit DPP attendance and reduce its effectiveness on outcomes. The proposed multidimensional, SD tailored DPP has great potential to be a feasible and scalable model to reduce DM risks among urban, African Americans and ultimately reduce DM disparities.

This description comes directly from the study's public registry record.

Talk to the study team

Christopher Winders  ·  18162355370  ·  windersc@umkc.edu

Carole Bowe Thompson  ·  8162356062  ·  bowethompsonc@umkc.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University HealthKansas City, Missouri, United StatesNot Yet Recruiting
University of Missouri-Kansas CityKansas City, Missouri, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05301413