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Study identifier: NCT05300685 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty

Condition: Urethral Stricture, Male  ·  Sponsor: University of California, San Francisco

PhasePhase 3
Planned participants60
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Patients undergoing buccal urethroplasty will often have significant post-operative oral pain from the graft site. Various graft harvest techniques and methods for post-harvest hemostasis including graft site closure have been explored. Despite the frequency of this clinical scenario there is no established best practice for peri-operative pain management in this patient population. In addition to traditional post operative pain control, groups have sought various peri-operative anesthetic regimens to improve post operative pain. This has led recently to the description of various regional blocks including buccal and periorbital blocks for peri-operative local anesthetic. No study has looked at superiority of regional pain management in this patient population. This study will aim to assess three established anesthetic protocols for oral pain control in a blinded, randomized controlled trial. Hypothesis: Patients who have buccal block will have lower post op pain without any increase adverse oral outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Lindsay A Hampson, MD  ·  415-353-2200  ·  lindsay.hampson@ucsf.edu

Sara Z Amare, BS  ·  (415) 514-7597  ·  sara.amare@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of California San FranciscoSan Francisco, California, United StatesRecruiting
MedStar UrologyWashington D.C., District of Columbia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05300685