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Study identifier: NCT05300308 Synced from ClinicalTrials.gov · July 29, 2026
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Lymphoedema and Nocturia/Nocturnal Polyuria After Pelvic LND for Urogenital Cancer

Condition: Urogenital Cancer · Lower Limb Lymphedema · Nocturia  ·  Sponsor: Universitaire Ziekenhuizen KU Leuven

PhaseN/A
Planned participants150
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

After the treatment of urogenital cancer, a person may develop lymphoedema of the leg(s) and/ or midline region. Clinical symptoms include abnormal tissue swelling, sensation of limb heaviness, erythema, pain, and impaired limb function. Lymphoedema can have a negative impact on quality of life (QoL) and the impact of lymphoedema on the cancer treatment decision making process is underestimated. A limited number of studies have evaluated the incidence rate of midline and leg lymphoedema after surgery for urogenital cancers and have investigated the prognostic variables. In addition, to the researchers knowledge, no evidence exists regarding which (combination of) clinical measuring methods are most sensitive to detect early lymphoedema at the lower limbs after the treatment of urogenital cancer. Therefore, in this prospective observational study, the epidemiology (i.e. incidence/ prevalence rate and prognostic variables) and the detection methods of lower limb lymphoedema after pelvic lymph node dissection for urogenital cancer will be investigated. Additionally, the epidemiology of nocturia and nocturnal polyuria will be studied (since this information is also missing in literature).

This description comes directly from the study's public registry record.

Talk to the study team

Nele Devoogdt, Prof. Dr.  ·  +3216342515  ·  nele.devoogdt@uzleuven.be

Charlotte Van Calster, MSc.  ·  charlotte.vancalster@kuleuven.be

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospitals Leuven, campus GasthuisbergLeuven, Flanders, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT05300308