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Study identifier: NCT05300269 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

SHR-1701 in Combination With Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer

Condition: Locally Advanced Rectal Cancer  ·  Sponsor: Suzhou Suncadia Biopharmaceuticals Co., Ltd.

PhasePhase 2
Planned participants73
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study will evaluate the efficacy and safety of SHR-1701 combined with radiotherapy and chemotherapy as perioperative treatment for locally advanced rectal cancer. Eligible patients will receive standard chemoradiation with SHR-1701 followed by XELOX combined with SHR-1701. In all subjects, restaging pelvic MRI with chest and abdominal CT will be performed after completion of neoadjuvant treatment to determine resectability and to rule out any evidence of metastases. Subjects who have resectable disease will undergo surgery. Adjuvant XELOX combined with SHR-1701 will be given after surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Qing Yang, M.D  ·  +86 021-61053363  ·  qing.yang@hengrui.com

Always discuss trial participation with your own doctor first.

Locations (1)

Fudan University Zhongshan HospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05300269