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Study identifier: NCT05299840 Synced from ClinicalTrials.gov · July 28, 2026
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Impact of Using the Oncogramme® Device to Select the First Line of Treatment for Patients With Metastatic Colorectal Cancer

Condition: Metastatic Colorectal Cancer  ·  Sponsor: Oncomedics

PhaseNA
Planned participants450
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Colorectal cancer is the 2nd leading cause of cancer death in France. Its incidence is nearly 45,000 new cases per year in 2017, with an estimated 5-year survival of 63% in 2015. Metastases are seen in 40-60% of colorectal cancer cases. The 5-year survival rate ranges from 5% to 15% for patients with widespread metastatic disease. Two types of treatments are used to treat colon cancer: surgery and medication protocol (chemotherapeutic drugs and targeted therapies). These treatments can be used alone or in combination. The current choice of a first line of chemotherapy is left to the practitioner's discretion, after consultation with a multidisciplinary consultation meeting. The choice of treatment(s) depends on official recommendations and is based on the results of clinical trials conducted on large populations, and takes into account the toxicities of the therapies used and the general condition of the patients. The therapeutic combinations for colorectal cancers are therefore multiple. However, to date, no consensus has been reached to ensure that each patient is treated effectively and as a unique case. Today, functional sensitivity tests offer the possibility for patients to be offered a personalized treatment against cancer. This is the case of the Oncogramme® device developed by Oncomedics, which is the first functional sensitivity test dedicated to oncology in Europe. It is based on an in vitro analysis of each patient's tumor cells in order to compare the response…

This description comes directly from the study's public registry record.

Talk to the study team

Christophe Lautrette, PhD  ·  0033 5 55 33 85 25  ·  c.lautrette@oncomedics.com

Stéphanie Giraud, PhD  ·  0033 5 55 33 85 25  ·  s.giraud@oncomedics.com

Always discuss trial participation with your own doctor first.

Locations (1)

Hôpital Saint Joseph MarseilleMarseille, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05299840