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Study identifier: NCT05296408 Synced from ClinicalTrials.gov · July 28, 2026
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Exoskeleton Research: Myoelectric Orthosis for Rehab of Severe Chronic Arm Motor Deficits

Condition: Chronic Stroke  ·  Sponsor: VA Office of Research and Development

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to 89 Years
Healthy volunteersNo

About this study

This study will evaluate the effects of combining motor learning-based therapy with use of the MyoPro , a wearable exoskeletal myoelectrically controlled orthotic device. MyoPro uses electromyographic (EMG) signals from the weak muscles to assist movement of the user's affected arm. The primary objective of this randomized controlled trial is to study the efficacy of using MyoPro in motor learning-based therapy for individuals with chronic stroke (\>6 months post) with severe upper limb motor deficits (Fugl-Meyer for Upper Limb score less than 30) compared with a similar dose of motor learning-based therapy alone. The secondary objectives are to evaluate neuroplasticity mechanisms, identify biomarkers of greater response to the intervention, and explore cost-effectiveness.

This description comes directly from the study's public registry record.

Talk to the study team

Jessica P McCabe, MPT DPT  ·  (216) 791-3800  ·  Jessica.Mccabe@va.gov

Svetlana Pundik, MD  ·  (216) 791-3800  ·  svetlana.pundik@va.gov

Always discuss trial participation with your own doctor first.

Locations (1)

Louis Stokes VA Medical Center, Cleveland, OHCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05296408