Condition: Cutaneous T-cell Lymphoma · Sponsor: Memorial Sloan Kettering Cancer Center
The researchers are doing this study to test the safety of combining bexarotene with TSEB radiotherapy in people who have a common form of CTCL called mycosis fungoides (MF). Bexarotene is a form of vitamin A that activates proteins called retinoid X receptors, which may stop the growth of cancer cells and kill them. TSEB radiotherapy is a type of radiation therapy that treats the entire surface of the skin with very low doses of radiation to kill cancer cells and shrink tumors. This type of radiation does not pass through the outer layers of the skin into the tissues and organs below the skin. The study researchers think that giving bexarotene treatment at the same time as treatment with TSEB radiotherapy may be more effective against MF than either treatment given alone or in sequence (one after the other).
This description comes directly from the study's public registry record.
Brandon Imber, MD, MS · 631-212-6346 · imberb@mskcc.org
Shamir Geller · gellers@mskcc.org
Always discuss trial participation with your own doctor first.
| Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities) | Commack, New York, United States | Recruiting |
| Memorial Sloan Kettering Cancer Center (All Protocol Activities) | New York, New York, United States | Recruiting |
| Memorial Sloan Kettering Nassau (Limited Protocol Activites) | Rockville Centre, New York, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05296304