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Study identifier: NCT05295680 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Oral Hymecromone to Treat Adolescents and Adults With Primary Sclerosing Cholangitis.

Condition: Primary Sclerosing Cholangitis  ·  Sponsor: Aparna Goel

PhasePhase 2
Planned participants24
Who can joinAll sexes, 14 Years to 75 Years
Healthy volunteersNo

About this study

Primary objective: To evaluate the efficacy of hymecromone plus standard of care compared with standard of care alone in the treatment of adolescents and adults with primary sclerosing cholangitis (PSC). Secondary objectives: To evaluate the change in Alkaline Phosphatase (ALP) from baseline to 6 months post-treatment following treatment with hymecromone plus standard of care compared with standard of care. To evaluate changes in biomarkers of PSC disease during hymecromone treatment, namely: (a) fibrotic effect (FibroScan); (b) inflammatory biomarkers (serum Hyaluronan (HA)); and, (c) T-cell count.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (2)

Stanford ClinicRedwood City, California, United StatesRecruiting
Stanford ClinicStanford, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05295680