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Study identifier: NCT05294731 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-Degrader

Condition: B-cell Malignancy · Non-Hodgkin Lymphoma · Mantle Cell Lymphoma  ·  Sponsor: BeiGene

PhasePhase 1/Phase 2
Planned participants146
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study aims to explore the recommended phase 2 dose and evaluate the safety, tolerability and preliminary antitumor activity of BGB-16673 monotherapy at the recommended Phase 2 dose for the selected B-cell malignancy expansion cohorts

This description comes directly from the study's public registry record.

Talk to the study team

BeiGene  ·  1.877.828.5568  ·  clinicaltrials@beigene.com

Always discuss trial participation with your own doctor first.

Locations (29)

The First Affiliated Hospital of Bengbu Medical UniversityBengbu, Anhui, ChinaRecruiting
Anhui Provincial HospitalHefei, Anhui, ChinaRecruiting
Peking University Third HospitalBeijing, Beijing Municipality, ChinaRecruiting
Beijing Chao Yang Hospital,Capital Medical UniversityBeijing, Beijing Municipality, ChinaRecruiting
Second Affiliated Hospital of Army Medical University (Xinqiao Hospital)Chongqing, Chongqing Municipality, ChinaRecruiting
Fujian Medical University Union HospitalFuzhou, Fujian, ChinaRecruiting
Sun Yat Sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting
Guangdong Provincial Peoples Hospital Huifu BranchGuangzhou, Guangdong, ChinaRecruiting
The Peoples Hospital of Guangxi Zhuang Autonomous RegionNanning, Guangxi, ChinaRecruiting
Nanyang Central HospitalNanyang, Henan, ChinaRecruiting
Henan Cancer HospitalZhengzhou, Henan, ChinaRecruiting
Union Hospital of Tongji Medical College, Huazhong University of Science and TechnologyWuhan, Hubei, ChinaRecruiting

+ 17 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05294731