← Eichor
Study identifier: NCT05289063 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Vascular Endothelial Dysfunction in Sleep Apnea

Condition: Obstructive Sleep Apnea of Adult  ·  Sponsor: Columbia University

PhasePhase 1
Planned participants110
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This double-blind placebo-controlled parallel group randomized study design will be used to test whether 4 weeks of atorvastatin 10 mg daily reduces levels of inflammatory markers in OSA patients treated with CPAP (standard of care). The purpose of this study is to investigate: 1) whether statins reduce endothelial inflammation and pro-thrombotic conditions in OSA, including in patients adherent to CPAP (Aim 1); and 2) whether statins reduce endothelial inflammation and pro-thrombotic conditions by improving endothelial cholesterol metabolism and trafficking in OSA (Aim 2).

This description comes directly from the study's public registry record.

Talk to the study team

Sanja Jelic, MD  ·  2125438875  ·  sj366@cumc.columbia.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Columbia University Irving Medical CenterNew York, New York, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05289063