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Study identifier: NCT05282654 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions

Condition: Multiple Chronic Conditions · Adverse Event  ·  Sponsor: Brigham and Women's Hospital

PhaseNA
Planned participants1300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study aims to predict and minimize post-discharge adverse events (AEs) during care transitions through early identification and escalation of patient-reported symptoms to inpatient and ambulatory clinicians by way of predictive algorithms and clinically integrated digital health apps. We will (1) develop and prospectively validate a predictive model of post-discharge AEs for patients with multiple chronic conditions (MCC); (2) combine, adapt, extend, and iteratively refine our EHR-integrated digital health infrastructure in a series of design sessions with patient and clinician participants; (3) conduct a RCT to evaluate the impact of ePRO monitoring on post-discharge AEs for MCC patients discharged from the general medicine service across Brigham Health; and (4) use mixed methods to evaluate barriers and facilitators of implementation and use as we develop a plan for sustainability, scale, and dissemination.

This description comes directly from the study's public registry record.

Talk to the study team

Anuj Dalal, MD  ·  (617) 525-8891  ·  adalal1@bwh.harvard.edu

Savanna Plombon, MPH  ·  857-307-2668  ·  splombon@bwh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Brigham and Women's Faulkner HospitalBoston, Massachusetts, United StatesRecruiting
Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05282654