← Eichor
Study identifier: NCT05280314 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors

Condition: Melanoma · Squamous Cell Carcinoma of Head and Neck  ·  Sponsor: IO Biotech

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter, multi-arm trial evaluating anti-tumor activity, safety, and immune infiltration of IO102-IO103 in combination with pembrolizumab KEYTRUDA® as neoadjuvant and post-surgery treatment. This proof-of-concept trial will include patients with resectable tumors in at least 2 indications.

This description comes directly from the study's public registry record.

Talk to the study team

Diane McDowell SVP, Clinical Development and Medical Affairs, MD  ·  +1 267 252 7296  ·  dmd@iobiotech.com

Shane O'Neill Clinical Program Director  ·  +44 790 433 7285  ·  son@iobiotech.com

Always discuss trial participation with your own doctor first.

Locations (15)

YaleNew Haven, Connecticut, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Massey Cancer CenterRichmond, Virginia, United StatesRecruiting
Melanoma Institute Australia The Uiniversity of Sydney, and Royal North Shore HospitalSydney, New South Wales, AustraliaRecruiting
Peter MacCallum Cancer CentreMelbourne, Victoria, AustraliaRecruiting
Aarhus University HospitalAarhus, DenmarkRecruiting
Copenhagen University Hospital HerlevCopenhagen, DenmarkRecruiting
CHRU LilleLille, FranceRecruiting
Hôpital Ambroise-ParéParis, FranceRecruiting
Institut Gustave RoussyParis, FranceRecruiting
Universitätsklinikum Essen & Research Alliance RuhrEssen, GermanyRecruiting
Universität Heidelberg, Medizinische FakultätHeidelberg, GermanyRecruiting

+ 3 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05280314