Condition: T-Cell Acute Lymphoblastic Leukemia · Sponsor: Shenzhen Geno-Immune Medical Institute
The purpose of this study is to determine the feasibility, safety, and efficacy of a combination therapy in the treatment of T-cell acute lymphoblastic leukemia (T-ALL): multi-antigen-targeted chimeric antigen receptor T cells (CAR-T) followed by engineered immune effector cytotoxic T cells (CTLs) and immune modified dendritic cell vaccine (DCvac). This approach is aimed to achieve NGS MRD negativity in T-ALL patients, which can identify a very low risk of relapse and define patients with possible long-term remission without further treatment.
This description comes directly from the study's public registry record.
Lung-Ji Chang, Ph.D · +86 0755-86573763 · c@szgimi.org
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| Shenzhen Geno-immune Medical Institute | Shenzhen, Guangdong, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05277753