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Study identifier: NCT05277558 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

Condition: Type2 Diabetes · Type 2 Diabetes Mellitus in Obese · Dysglycemia  ·  Sponsor: Washington University School of Medicine

PhaseN/A
Planned participants117
Who can joinAll sexes, 12 Years to 17 Years
Healthy volunteersYes

About this study

Investigators propose to study youth across the spectrum of body mass index (BMI) and dysglycemia. This approach will allow investigators to disentangle the relationship of key features of type 2 diabetes (T2D) risk (e.g. obesity) with intermediary physiologic changes (e.g. insulin resistance, inflammation, β-cell dysfunction and dysglycemia) that pose a risk for the brain. Investigators will determine which of these factors are most associated with differences in brain structure and function among groups, over time, and how these effects differ from normal neurodevelopment.

This description comes directly from the study's public registry record.

Talk to the study team

Mary Borgschulte, RN, BSN, CDE  ·  314-952-8195  ·  Mary.b@wustl.edu

Kaeli Spight  ·  314-362-4721  ·  kspight@wustl.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Washington University School of MedicineSt Louis, Missouri, United StatesRecruiting
UPMC Children's Hospital of PittsburghPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05277558