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Study identifier: NCT05268887 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

High Frequency Light, Sound, and Tactile Stimulation to Improve Motor and Cognitive Deficits in Parkinson's Disease

Condition: Parkinson Disease  ·  Sponsor: Massachusetts Institute of Technology

PhaseNA
Planned participants40
Who can joinAll sexes, 45 Years to 90 Years
Healthy volunteersNo

About this study

Parkinson's disease (PD) impacts different types of neural oscillations in the brain, including beta (13-30Hz) and gamma oscillations (30-80Hz), which contributes to PD's cardinal symptoms of resting tremor, rigidity, bradykinesia (slowness of movement), and gait instability. The investigators' lab has developed a non-invasive method of increasing gamma power in the brain using Gamma Entrainment Using Sensory Stimulation (GENUS) through light, sound, and tactile stimulation devices. For this study, 40 participants with mild Parkinson's disease will be recruited, and the investigators will assess their brain waves with electroencephalogram (EEG) before, during, and after light, sound, and tactile stimulation to determine the safety, feasibility, and optimization of GENUS as a potential therapy in the PD population.

This description comes directly from the study's public registry record.

Talk to the study team

gamma wave  ·  617-258-7723  ·  gamma.wave@mit.edu

Ana Trisini Lipsanopoulos, BS  ·  617-258-7723  ·  anat13@mit.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Massachusetts Institute of TechnologyCambridge, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05268887