Condition: Posttraumatic Stress Disorder · Sponsor: VA Office of Research and Development
Although effective treatments for PTSD exist, high rates of treatment dropout and sub-optimal response rates remain common. Incorporating family members in treatment represents one avenue for improving outcomes and providing Veteran-centered care, and surveys of Veterans in outpatient VA PTSD care indicate that 80% desire family involvement. The VA has invested many years and millions of dollars on the dissemination of Cognitive Processing Therapy (CPT) and Prolonged Exposure (PE) for PTSD. A family-based intervention that complements these two first-line treatments would capitalize on existing treatment infrastructure while also potentially boosting outcomes and retention. Preliminary testing of the proposed Brief Family Intervention (BFI) resulted in 50% less dropout from CPT/PE among Veterans whose family members received the BFI. There was also a large impact on PTSD symptoms at 16 weeks (d = 1.12) in favor of the BFI group. The goal of this study is to test the effectiveness of the BFI among a fully-powered sample. One hundred Veteran-family member dyads (n = 200) will be recruited. Veterans will be beginning a course of usual-care CPT or PE at one of two VA sites. Family members will be randomized to receive or not receive the BFI, a two-session psychoeducational and skills-based protocol. PTSD symptom severity and treatment retention will be the primary outcomes. Assessments will be conducted by independent evaluators at baseline, 6-, 12-, 18-, and 26-weeks. Veterans …
This description comes directly from the study's public registry record.
Johanna Thompson-Hollands, PhD · (857) 364-2067 · Johanna.Thompson-Hollands@va.gov
Cameron Busser, BA · (857) 364-4143 · cameron.busser@va.gov
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| VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA | Boston, Massachusetts, United States | Recruiting |
| Durham VA Medical Center, Durham, NC | Durham, North Carolina, United States | Recruiting |
| Cincinnati VA Medical Center, Cincinnati, OH | Cincinnati, Ohio, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05267665