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Study identifier: NCT05266976 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Mode of Exercise and Bone Biomarkers in Older Veterans

Condition: Aging · Musculoskeletal Diseases · Osteoporosis  ·  Sponsor: VA Office of Research and Development

PhaseNA
Planned participants120
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersYes

About this study

Adults are often encouraged to exercise to maintain or improve bone health. However, there is evidence that exercise does not always lead to increases in bone mass, and exercise could lead to bone loss under certain conditions. Endurance exercise can increase bone resorption following an exercise bout, which may explain why bone does not always favorably adapt to exercise, but it is unclear if this also happens with resistance exercise. Further, it is not known how exercise training influences blood markers of bone resorption for either endurance or resistance exercise. The purpose of this study is to determine 1) if resistance exercise causes a similar increase in bone resorption as endurance exercise; and 2) if exercise training influences the increase in bone resorption following exercise for both endurance and resistance exercise.

This description comes directly from the study's public registry record.

Talk to the study team

Sarah J Wherry, PhD  ·  (720) 848-6475  ·  sarah.wherry@va.gov

Toby Wellington, MS  ·  (720) 848-6376  ·  toby.wellington@va.gov

Always discuss trial participation with your own doctor first.

Locations (1)

Rocky Mountain Regional VA Medical Center, Aurora, COAurora, Colorado, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05266976