Condition: Clostridioides Difficile Infection · Sponsor: Benoit Guery
The clinical trial aims to evaluate the efficacy of fecal microbiota transplantation (FMT) after standard of care treatment (either vancomycin or fidaxomicin) vs the pragmatic use of standard of care treatment (either vancomycin or fidaxomicin) in severe and non-severe first episode and first recurrence of Clostridioides difficile infection (CDI). Experimental arm: antibiotic treatment (vancomycin or fidaxomicin as initially prescribed per SoC continued for 10 days) followed by FMT by oral capsules (one FMT, i.e. 20 FMT capsules given on 2 consecutive days, and followed by a 2nd FMT in severe CDI). Control Arm: vancomycin or fidaxomicin as initially prescribed per SoC continued for 10 days.
This description comes directly from the study's public registry record.
Benoit Guery, MD · +41213141643 · benoit.guery@chuv.ch
Project Manager · +41795564371 · crc.fender@chuv.ch
Always discuss trial participation with your own doctor first.
| Universitätsspital | Basel, Basel, Switzerland | Recruiting |
| Inselspital Bern | Bern, Canton of Bern, Switzerland | Recruiting |
| HFR Fribourg - Hôpital cantonal | Fribourg, Canton of Fribourg, Switzerland | Recruiting |
| Hirslanden Klinik St Anna | Lucerne, Canton of Lucerne, Switzerland | Recruiting |
| Kantonsspital St Gallen, HOCH | Sankt Gallen, Canton of St. Gallen, Switzerland | Recruiting |
| CHUV | Lausanne, Canton of Vaud, Switzerland | Recruiting |
| Universitätsspital Zürich | Zurich, Canton of Zurich, Switzerland | Recruiting |
| Institut central des hôpitaux | Sion, Valais, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05266807