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Study identifier: NCT05265273 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis

Condition: Myasthenia Gravis  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 2/Phase 3
Planned participants12
Who can joinAll sexes, 2 Years to 17 Years
Healthy volunteersNo

About this study

The purpose of this study is to determine the effect of nipocalimab on total serum immunoglobulin G (IgG) in pediatric participants 2 to less than (\<) 18 years of age (globally) and 8 to \<18 years of age (for Unites Stated (US) sites only), the safety and tolerability of treatment with nipocalimab in children and adolescents and to evaluate the pharmacokinetics (PK) of nipocalimab in children and adolescents with generalized myasthenia gravis (gMG) who have an insufficient clinical response to ongoing, stable standard-of-care therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (19)

Phoenix Children's HospitalPhoenix, Arizona, United StatesRecruiting
Childrens Hospital Los AngelesLos Angeles, California, United StatesCompleted
Lucile Packard Children's Hospital StanfordPalo Alto, California, United StatesRecruiting
UCSF Benioff Children's HospitalSan Francisco, California, United StatesRecruiting
Children's Hospital ColoradoAurora, Colorado, United StatesRecruiting
University of South Florida Morsani Center for Advanced HealthcareTampa, Florida, United StatesRecruiting
University of Kansas Medical CenterLawrence, Kansas, United StatesCompleted
C.S. Mott Children's HospitalAnn Arbor, Michigan, United StatesRecruiting
Penn State Milton S Hershey Medical CtrHershey, Pennsylvania, United StatesRecruiting
Childrens Hospital Of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting
University of Pittsburgh Medical CenterPittsburgh, Pennsylvania, United StatesTerminated
Nagano Children's HospitalAzumino-shi, JapanRecruiting

+ 7 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05265273