Condition: Mayer Rokitansky Kuster Hauser Syndrome · Absence of Uterus · Infertility of Uterine Origin · Sponsor: John Goss
Absolute Uterine Factor Infertility (AUFI) is due to congenital or surgical absence of a uterus or the presence of a nonfunctional uterus. Until 2014, the only option for women affected by Absolute Uterine Factor Infertility (AUFI) was adoption or surrogate motherhood. Uterine transplant is a new form of transplant to treat AUFI. The technique of uterus transplant was developed in Sweden with the transplantation of the uterus from a living donor to a woman affected by AUFI. Approximately 80 uterine transplantations have been performed, more than 50 of which have occurred within the past 3 years. To date, 34 children have been born from mothers who have received a living donor uterine transplant. This is a prospective study to treat Absolute Uterine Factor Infertility (AUFI) through uterine transplantation utilizing a uterus from a living or deceased donor resulting in live birth. A total of 10 biologically female (XX Karyotype) subjects will receive a uterine transplant.
This description comes directly from the study's public registry record.
Transplant Services Coordinator · 832-822-1551 · uterustransplant@texaschildrens.org
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| Texas Children's Hospital | Houston, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05263076