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Study identifier: NCT05261139 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

Condition: COVID-19  ·  Sponsor: Pfizer

PhasePhase 3
Planned participants160
Who can joinAll sexes, 0 Years to 17 Years
Healthy volunteersNo

About this study

The purpose of this clinical trial is to learn about the safety, pharmacokinetics (pharmacokinetics helps us understand how the drug is changed and eliminated from your body after you take it), and efficacy (how well a study treatment works in the study) of the study medicine (called nirmatrelvir/ritonavir) for potential treatment of coronavirus disease 2019 (COVID-19). The study medicine will be given to patients under 18 years of age with COVID-19 that are not hospitalized but are at risk for severe disease.

This description comes directly from the study's public registry record.

Talk to the study team

Pfizer CT.gov Call Center  ·  1-800-718-1021  ·  ClinicalTrials.gov_Inquiries@pfizer.com

Always discuss trial participation with your own doctor first.

Locations (73)

Phoenix Children's HospitalPhoenix, Arizona, United StatesActive Not Recruiting
Children's Hospital Los AngelesLos Angeles, California, United StatesActive Not Recruiting
Kaiser PermanenteLos Angeles, California, United StatesActive Not Recruiting
UCLA David Geffen School of MedicineLos Angeles, California, United StatesNot Yet Recruiting
UCLALos Angeles, California, United StatesNot Yet Recruiting
Children's National Medical CenterWashington D.C., District of Columbia, United StatesActive Not Recruiting
Life Spring Research FoundationMiami, Florida, United StatesRecruiting
Children's Healthcare of Atlanta - Arthur M. Blank HospitalAtlanta, Georgia, United StatesRecruiting
Rophe Adult and Pediatric Medicine/SKYCRNGUnion City, Georgia, United StatesTerminated
Ann & Robert H. Lurie Children's Hospital of ChicagoChicago, Illinois, United StatesActive Not Recruiting
University of Chicago Medical CenterChicago, Illinois, United StatesRecruiting
Louisiana State University Health Sciences ShreveportShreveport, Louisiana, United StatesRecruiting

+ 61 more locations — full list on the registry record.

Follow this study

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Source record: clinicaltrials.gov/study/NCT05261139