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Study identifier: NCT05260541 Synced from ClinicalTrials.gov · July 28, 2026
● Terminated

A Clinical Trial of PRAX-114 in Participants With Post-Traumatic Stress Disorder

Condition: Post-traumatic Stress Disorder · Post Traumatic Stress Disorder · Stress Disorder  ·  Sponsor: Praxis Precision Medicines

PhasePhase 2
Planned participants11
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This trial is comprised of a 4-week randomized, double-blind, placebo-controlled treatment period followed by an optional 8-week open-label extension (OLE) period. This trial will evaluate the efficacy and safety of oral PRAX-114 flexibly dosed at 40 to 60 mg for 4 weeks compared to placebo in adults with PTSD. The OLE period consisting of treatment with 40 mg PRAX-114 for 8 weeks will provide additional efficacy and safety data.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (17)

Praxis Research SitePhoenix, Arizona, United States
Praxis Research SiteLittle Rock, Arkansas, United States
Praxis Research SiteRogers, Arkansas, United States
Praxis Research SiteLemon Grove, California, United States
Praxis Research SiteWestlake Village, California, United States
Praxis Research SiteFort Myers, Florida, United States
Praxis Research SiteDecatur, Georgia, United States
Praxis Research SiteBoston, Massachusetts, United States
Praxis Research SiteLas Vegas, Nevada, United States
Praxis Research SiteCincinnati, Ohio, United States
Praxis Research SiteDayton, Ohio, United States
Praxis Research SiteOklahoma City, Oklahoma, United States

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05260541