Condition: Food Allergy · Food Hypersensitivity · Sponsor: University of Erlangen-Nürnberg Medical School
Aim of the study is to improve the diagnosis of food allergy and hypersensitivity. Intestinal homogenates will be used to determine total IgE, specific IgE, tryptase, histamine and inflammation parameters (IFNgamma, TNFalpha). These data will be correlated with serum values and disease status. In addition, organoids from duodenal tissue will be isolated and cultured in vitro and stimulated with the major food allergens. The gene and protein expression will be checked to identify relevant biomarkers.
This description comes directly from the study's public registry record.
Yurdagül Zopf, Prof · +4991318545218 · yurdaguel.zopf@uk-erlangen.de
Walburga Dieterich, Dr · +4991318535128 · walburga.dieterich@uk-erlangen.de
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| Department of Medicine 1, Hector Center for Nutrition, Exercise and Sports, Friedrich-Alexander-University Erlangen-Nuremberg | Erlangen, Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05259826