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Study identifier: NCT05257681 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction

Condition: Emphysema or COPD  ·  Sponsor: Beth Israel Deaconess Medical Center

PhaseNA
Planned participants20
Who can joinAll sexes, 40 Years to 75 Years
Healthy volunteersNo

About this study

The purpose of this protocol is to perform a pilot prospective controlled clinical trial to evaluate the potential role of lung fissure completion with pleural adhesiolysis strategy (experimental intervention) in severe emphysema/COPD patients with failed bronchoscopic lung volume reduction (BLVR) via the use of endobronchial valves (EBVs) therapy. In select patients, the lung fissure completion with adhesiolysis strategy will be performed by video-assisted thoracoscopic surgery (VATS) guided stapling along the lung fissures to reduce collateral ventilation with adhesions removal and determine whether this experimental strategy will improve outcomes after failed BLVR in patients with severe emphysema/COPD.

This description comes directly from the study's public registry record.

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Locations (1)

Beth Israel Deaconess Medical CenterBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05257681