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Study identifier: NCT05256641 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma

Condition: Diffuse Large B-Cell Lymphoma · High-grade B-cell Lymphoma · Transformed Lymphoma  ·  Sponsor: Jonsson Comprehensive Cancer Center

PhasePhase 1/Phase 2
Planned participants24
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This phase Ib/II trial studies the side effects and efficacy of maintenance acalabrutinib following cellular therapy in treating patients with large B-cell lymphoma at very high risk of the cancer coming back. Acalabrutinib is a small molecular inhibitor that may interfere with the ability of cancer cells to grow and spread.

This description comes directly from the study's public registry record.

Talk to the study team

Vlad Kustanovitch  ·  310-206-5756  ·  VKustanovich@mednet.ucla.edu

Always discuss trial participation with your own doctor first.

Locations (3)

UCLA / Jonsson Comprehensive Cancer CenterLos Angeles, California, United StatesRecruiting
University of California Davis Comprehensive Cancer CenterSacramento, California, United StatesRecruiting
University of OklahomaOklahoma City, Oklahoma, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05256641