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Study identifier: NCT05255471 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

MITO 35B: Olaparib Beyond Progression Compared to Platinum Chemotherapy After Secondary Cytoreductive Surgery in Recurrent Ovarian Cancer Patients.

Condition: Ovarian Cancer  ·  Sponsor: National Cancer Institute, Naples

PhasePhase 3
Planned participants200
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

MITO 35b is designed as randomized, open label, phase III trial that aims to assess the efficacy of olaparib maintenance beyond progression compered to standard platinum-based chemotherapy after secondary cytoreductive surgery. The target population of this study are ovarian cancer patients who experience a disease recurrence or progression to a first line maintenance therapy with PARPi; at progression patients must have received a secondary cytoreduction according to clinical practice.

This description comes directly from the study's public registry record.

Talk to the study team

Clorinda Schettino, MD  ·  003908159031791  ·  c.schettino@istitutotumori.na.it

Sandro Pignata, MD  ·  00390815903409  ·  s.pignata@istitutotumori.na.it

Always discuss trial participation with your own doctor first.

Locations (1)

IRCCS Istituto Nazionale Tumori di NapoliNaples, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05255471