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Study identifier: NCT05254171 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer

Condition: Pancreatic Cancer Metastatic · Pancreatic Ductal Adenocarcinoma · Pancreatic Cancer Stage IV  ·  Sponsor: Panbela Therapeutics, Inc.

PhasePhase 2/Phase 3
Planned participants600
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study is a randomized, double-blind, placebo-controlled, multicenter study of standard treatment with nab-paclitaxel and gemcitabine with or without SBP-101 in subjects previously untreated for metastatic pancreatic ductal adenocarcinoma (PDA), including subjects who have received prior neoadjuvant or adjuvant treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Rachel Bragg, MPH  ·  952-479-1196  ·  rbragg@panbela.com

Tammy Groene  ·  952-479-1196  ·  tgroene@panbela.com

Always discuss trial participation with your own doctor first.

Locations (93)

Genesis Cancer and Blood Institute (SCRI)Hot Springs, Arkansas, United StatesWithdrawn
Providence Medical FoundationFullerton, California, United StatesRecruiting
Yale Cancer CenterNew Haven, Connecticut, United StatesRecruiting
MedStar Georgetown University HospitalWashington D.C., District of Columbia, United StatesActive Not Recruiting
Henry Ford Health SystemDetroit, Michigan, United StatesRecruiting
CentraCare HealthSaint Cloud, Minnesota, United StatesWithdrawn
Columbia University Medical CenterNew York, New York, United StatesRecruiting
University of RochesterRochester, New York, United StatesRecruiting
Mark H Zangmeister Center - SCRI - PPDSColumbus, Ohio, United StatesTerminated
Tennessee Oncology NASH - SCRI - PPDSNashville, Tennessee, United StatesActive Not Recruiting
HOPE Cancer Center of East TexasTyler, Texas, United StatesRecruiting
Medical Oncology Associates - SpokaneSpokane, Washington, United StatesRecruiting

+ 81 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05254171