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Study identifier: NCT05246098 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

REVIVe: Frailty, Rehabilitation, and Outcomes in Critically Ill Adult and Pediatric Survivors of COVID-19 or ARI

Condition: Respiratory Disease · COVID-19 · Viral Infection  ·  Sponsor: McMaster University

PhaseN/A
Planned participants900
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

Background: Many adults and some children with COVID-19 or acute respiratory infection become critically ill and need advanced life support in the Intensive Care Unit (ICU). Frailty is a medical condition of reduced function and health. Adults with frailty have a lower chance of surviving critical illness. The investigators are still learning about critically ill adults with COVID-19 or acute respiratory infection, and do not have much information on how frailty affects outcomes in critically ill children, with or without COVID-19 or acute respiratory infection. Rehabilitation can help survivors of COVID-19 or acute respiratory infection by improving strength and improve quality of life (QOL). Objectives: The main goal of this research study is to see if patients with frailty have a lower chance of surviving COVID-19 or acute respiratory infection critical illness and more health problems after survival than patients without frailty. The investigators will also study the types of rehabilitation received by patients with COVID-19 or acute respiratory infection. Methods: The investigators will include adults and children with COVID-19 or acute respiratory infection who are admitted to the ICUs that participate in the study. The investigators will gather data about each patient, including before and during their illness. Outcomes: The investigators will collect level of frailty, function, and types of therapy, or rehabilitation received by patients. In adults, the investigato…

This description comes directly from the study's public registry record.

Talk to the study team

Geoff Strong, PT, MS  ·  905-522-1155  ·  revive@mcmaster.ca

Always discuss trial participation with your own doctor first.

Locations (28)

Alberta Children's HospitalCalgary, Alberta, CanadaActive Not Recruiting
University of AlbertaEdmonton, Alberta, CanadaRecruiting
Sturgeon Community HopsitalSt. Albert, Alberta, CanadaNot Yet Recruiting
Royal Columbian HospitalNew Westminster, British Columbia, CanadaNot Yet Recruiting
Children's Hospital of WinnipegWinnipeg, Manitoba, CanadaActive Not Recruiting
QEII Health Sciences CentreHalifax, Nova Scotia, CanadaRecruiting
Izaak Walton Killam Hospital for ChildrenHalifax, Nova Scotia, CanadaRecruiting
Brantford General HospitalBrantford, Ontario, CanadaRecruiting
Hamilton General HospitalHamilton, Ontario, CanadaRecruiting
St. Joseph's Healthcare Intensive Care UnitHamilton, Ontario, CanadaRecruiting
McMaster Children's HospitalHamilton, Ontario, CanadaActive Not Recruiting
Juravinski HospitalHamilton, Ontario, CanadaRecruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05246098