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Study identifier: NCT05245227 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Double Simultaneous Uterotonic Agents Versus Single Agent Regimen to Prevent Early Postpartum Hemorrhage

Condition: Postpartum Hemorrhage  ·  Sponsor: Stony Brook University

PhasePhase 3
Planned participants1358
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersYes

About this study

To determine the effectiveness of using two medications simultaneously versus one medication, as is standard of care, in preventing early postpartum hemorrhage. There have been studies that looked at giving two medications and that there were reduced odds of postpartum hemorrhage. Specific Aim 1: Determine if double simultaneous uterotonic agent regimen (misoprostol and oxytocin) is superior to single agent (oxytocin only) in reducing postpartum hemorrhage. Specific Aim 2: Determine any potential side effects of a double simultaneous uterotonic agentregimen (misoprostol and oxytocin) versus a single agent (oxytocin only).

This description comes directly from the study's public registry record.

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Locations (1)

Stony Brook UniversityStony Brook, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05245227