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Study identifier: NCT05241249 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Stimulation With Bethanechol in Combination With Gemcitabine and Nab-paclitaxel in Pancreatic Adenocarcinoma

Condition: Pancreas Cancer  ·  Sponsor: Susan E. Bates

PhasePhase 2
Planned participants37
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objective of this study is to assess the impact of bethanechol therapy on R0 resection rates. The safety objective will be assessment of the safety and tolerability of bethanechol in combination with gemcitabine and nab-paclitaxel. The exploratory objective will be to evaluate genomic biomarkers associated with parasympathetic stimulation in pancreatic cancer, and the ability to reduce tumor growth rate.

This description comes directly from the study's public registry record.

Talk to the study team

Research Nurse Navigator  ·  212-342-5162  ·  cancerclinicaltrials@cumc.columbia.edu

Susan E Bates, MD  ·  seb2227@cumc.columbia.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Columbia University Medical CenterNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05241249