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Study identifier: NCT05240976 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Combination of NMDA-enhancing and Anti-inflammatory Treatments for Ultra-resistant Schizophrenia

Condition: Schizophrenia  ·  Sponsor: China Medical University Hospital

PhasePhase 2
Planned participants80
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Previous study found that some NMDA-enhancing agent was able to augment efficacy of clozapine for clinical symptoms but not cognitive function in the treatment of ultra-resistant schizophrenia. In addition, several drugs with anti-inflammatory properties have been tested in clinical trials for the treatment of schizophrenia. Whether a drug with anti-inflammatory property can strengthen the efficacy of an NMDA-enhancer (NMDAE) in the treatment of ultra-resistant schizophrenia remains unknown.

This description comes directly from the study's public registry record.

Talk to the study team

Hsien-Yuan Lane, M.D., Ph.D  ·  886 4 22052121  ·  hylane@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Psychiatry, China Medical University HospitalTaichung, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT05240976