Condition: Obsessive Compulsive Disorder (OCD) · Comorbid Post-Traumatic Stress Disorder and OCD · Sponsor: VA Office of Research and Development
Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherapy for OCD; however, no randomized controlled trials (RCTs) have examined the effectiveness of ERP among Veterans or individuals with both OCD and posttraumatic stress disorder (PTSD). This 4-year Hybrid Type I trial will compare outcomes of ERP to those of a control condition among Veterans with OCD. Primary and secondary aims will examine whether Veterans' functioning, quality of life, and OCD symptoms differ between the ERP and control in the full sample of Veterans with OCD, and in the half of the sample with both OCD and PTSD. The tertiary aim is to conduct a mixed-methods formative evaluation of the implementation potential of ERP in VA mental health settings.
This description comes directly from the study's public registry record.
Terri L Fletcher, PhD · (713) 440-4400 · Terri.Fletcher@va.gov
Matthew G Escamilla, BS · (713) 440-4461 · matthew.escamilla@va.gov
Always discuss trial participation with your own doctor first.
| East Orange Campus of the VA New Jersey Health Care System, East Orange, NJ | East Orange, New Jersey, United States | Recruiting |
| VA Western New York Healthcare System, Buffalo, NY | Buffalo, New York, United States | Recruiting |
| VA NY Harbor Healthcare System, New York, NY | New York, New York, United States | Recruiting |
| Northport VA Medical Center, Northport, NY | Northport, New York, United States | Recruiting |
| James J. Peters VA Medical Center, Bronx, NY | The Bronx, New York, United States | Recruiting |
| Asheville VA Medical Center, Asheville, NC | Asheville, North Carolina, United States | Recruiting |
| Durham VA Medical Center, Durham, NC | Durham, North Carolina, United States | Recruiting |
| Fayetteville VA Medical Center, Fayetteville, NC | Fayetteville, North Carolina, United States | Recruiting |
| Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC | Salisbury, North Carolina, United States | Recruiting |
| VA Roseburg Healthcare System, Roseburg, OR | Roseburg, Oregon, United States | Recruiting |
| VA Southern Oregon Rehabilitation Center and Clinics, White City, OR | White City, Oregon, United States | Recruiting |
| Ralph H. Johnson VA Medical Center, Charleston, SC | Charleston, South Carolina, United States | Recruiting |
+ 7 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05240924