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Study identifier: NCT05239546 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers

Condition: Colon Cancer · dMMR Colorectal Cancer  ·  Sponsor: University of Iowa

PhasePhase 2
Planned participants25
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase II, single arm study looking at the rate of major clinical response and non-operative management in Stage II and III colon cancer after 18 weeks (up to 6 cycles) of neoadjuvant dostarlimab.

This description comes directly from the study's public registry record.

Talk to the study team

Saima Sharif, MD, MS  ·  319-356-1616  ·  saima-sharif@uiowa.edu

Alisha Demsky  ·  319-384-5461  ·  alisha-demsky@uiowa.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of Iowa Hospitals & ClinicsIowa City, Iowa, United StatesRecruiting
University of WisconsinMadison, Wisconsin, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05239546