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Study identifier: NCT05236972 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer

Condition: Colorectal Carcinoma  ·  Sponsor: Sun Yat-sen University

PhasePhase 3
Planned participants323
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

In this open-label phase III study, patients with local advanced colon cancer (TanyN+ ,M0, dMMR/MSI-H, at least 10cm from the anus verge)will be scheduled to Group A: receive anti-PD-1 antibody alone (8 cycles, 200mg iv drip Q3W) and Group B (4 or 8 cycles of XELOX: oxaliplatin 130mg/m2 day 1, capecitabine 2000mg/m2 days 1-14, repeated every 21 days). The primary endpoint was 3 Disease-free survival; analyses were done based on all patients with post-randomization data.

This description comes directly from the study's public registry record.

Talk to the study team

Peirong Ding, professor  ·  +86-13543478645  ·  dingpr@sysucc.org.cn

Zhenlin Hou  ·  +86-17612057762  ·  houzl@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen UniversityGuangzhou, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05236972