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Study identifier: NCT05230173 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

Condition: Ulcerative Colitis · Crohn Disease  ·  Sponsor: University of California, San Diego

PhaseNA
Planned participants250
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to compare the effectiveness and safety of a strategy of switching to an alternative targeted immunomodulator (TIM) therapy to treat to a target of endoscopic remission, versus continuing index TIM in patients with inflammatory bowel disease (IBD) (Crohn's disease or ulcerative colitis \[UC\]) in symptomatic remission with moderate to severe endoscopic inflammation despite optimization of index TIM in a real-world setting.

This description comes directly from the study's public registry record.

Talk to the study team

Siddharth Singh, MD  ·  858-246-2352  ·  sis040@health.ucsd.edu

Jason Hou, MD  ·  713-798-8220  ·  jkhou@bcm.edu

Always discuss trial participation with your own doctor first.

Locations (22)

Hoag HospitalIrvine, California, United StatesRecruiting
UC San Diego HealthLa Jolla, California, United StatesRecruiting
Cedars-SinaiLos Angeles, California, United StatesRecruiting
Sutter HealthPalo Alto, California, United StatesRecruiting
University of ColoradoAurora, Colorado, United StatesRecruiting
Yale UniversityNew Haven, Connecticut, United StatesRecruiting
MedStar Georgetown University HospitalWashington D.C., District of Columbia, United StatesRecruiting
Mayo Clinic JacksonvilleJacksonville, Florida, United StatesRecruiting
University of Chicago MedicineChicago, Illinois, United StatesRecruiting
Dartmouth HitchcockLebanon, New Hampshire, United StatesRecruiting
Saratoga Schenectady Gastroenterology AssociatesBurnt Hills, New York, United StatesRecruiting
NYU Langone HealthNew York, New York, United StatesRecruiting

+ 10 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05230173