Condition: Anti Phospholipid Syndrome · Sponsor: Peking Union Medical College Hospital
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by thrombosis and pregnancy morbidity in patients with persistently positive antiphospholipid antibodies (aPLs). However, large-scale research on general population with persistent aPLs has been lacking. This project proposes to establish the first multicenter cohort of patients with persistently positive aPLs in China and conduct a comprehensive clinical phenotyping study. Based on traditional phenotypes of thrombotic and pregnancy events, the focus will be on extra-standard clinical phenotypes and prospective assessment of event risk and prognosis in aPL-positive population. A prospective analysis of extra-standard antibodies will also be conducted to recommend detection criteria for extra-standard antibody application in China and to assess their clinical significance.
This description comes directly from the study's public registry record.
Jiuliang Zhao, M.D. · 0086-13810103105 · Jiuliang.zhao@cstar.org.cn
Yangzhong Zhou, M.D. · zhouyangzhong@pumch.cn
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| Peking Union Medical College Hospital | Beijing, Beijing Municipality, China | Recruiting |
| Beijing Shunyi Hospital | Beijing, Beijing Municipality, China | Recruiting |
| Fujian Medical University Union Hospital | Fuzhou, Fujian, China | Recruiting |
| The Third Affiliated Hospital of Guangzhou Medical University | Guangzhou, Guangdong, China | Recruiting |
| Shenzhen People's Hospital | Shenzhen, Guangdong, China | Recruiting |
| The Second People's Hospital of Shenzhen | Shenzhen, Guangdong, China | Recruiting |
| The First Affiliated Hospital of Guangxi Medical University | Nanning, Guangxi, China | Recruiting |
| The Affilicated Hospital of Inner Mongolia Medical University | Hohhot, Inner Mongolia, China | Recruiting |
| Jiangsu Province Hospital | Nanjing, Jiangsu, China | Recruiting |
| The Second Affiliated Hospical of Nanchang University | Nanchang, Jiangxi, China | Recruiting |
| The Second Affiliated Hospital of Dalian Medical University | Dalian, Liaoning, China | Recruiting |
| The First Hospital of China Medical University | Shenyang, Liaoning, China | Recruiting |
+ 6 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05230017