Condition: Preterm Birth · Inflammation · Stress · Sponsor: Columbia University
Pregnancy ends in preterm birth (PTB) for approximately 1 in 10 women, though more often for Non-Hispanic Black women, 14.12% PTB rate, compared to 9.09% for Non-Hispanic White women. Psychosocial stress and childhood trauma each are associated with risk for PTB and PTB has an intergenerational impact: mothers born preterm are more likely to give birth preterm, especially amongst Black women. In this project, we will study mitochondria, which contain their own genome, the mitochondria DNA, and are inherited from the mother, as they represent a potential intersection point between psychosocial experiences and their biological embedding in underlying disease outcomes such as PTB
This description comes directly from the study's public registry record.
Catherine Monk, PhD · 646-774-8941 · cem31@cumc.columbia.edu
Elizabeth Werner, PhD · 646-774-8835 · ew150@cumc.columbia.edu
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| Columbia University Irving Medical Center | New York, New York, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05229666