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Study identifier: NCT05227326 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

AOH1996 for the Treatment of Refractory Solid Tumors

Condition: Refractory Malignant Solid Neoplasm · Osteosarcoma · Leiomyosarcomas  ·  Sponsor: City of Hope Medical Center

PhasePhase 1
Planned participants92
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase I trial studies the side effects and best dose of AOH1996 in treating patients with solid tumors that do not respond to treatment (refractory). AOH1996 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

This description comes directly from the study's public registry record.

Talk to the study team

Vincent Chung, MD  ·  6262184673  ·  vchung@coh.org

Always discuss trial participation with your own doctor first.

Locations (3)

Honor Health Research and Innovation InstituteScottsdale, Arizona, United StatesNot Yet Recruiting
City of Hope Medical CenterDuarte, California, United StatesRecruiting
City of Hope at Long Beach ElmLong Beach, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05227326