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Study identifier: NCT05224401 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pivmecillinam With Amoxicillin/Clavulanic Acid for Step Down Oral Therapy in ESBL UTIs

Condition: Urinary Tract Infections · Bacteremia · Antibiotic Resistant Infection  ·  Sponsor: Lund University

PhasePhase 3
Planned participants330
Who can joinAll sexes, 18 Years to 130 Years
Healthy volunteersNo

About this study

To evaluate if the combination of pivmecillinam and clavulanic acid (PAC) is non-inferior to ciprofloxacin, trimethoprim-sulfamethoxazole or ertapenem as step down oral therapy in patients with febrile UTI caused by extended spectrum beta-lactamase (ESBL) producing Enterobacterales (EPE).

This description comes directly from the study's public registry record.

Talk to the study team

Oskar Ljungquist, M.D, PhD  ·  +46424063182  ·  oskar.ljungquist@med.lu.se

Jonas Tverring, M.D, PhD  ·  +46424062673  ·  jonas.tverring@med.lu.se

Always discuss trial participation with your own doctor first.

Locations (5)

Helsingborg hospitalHelsingborg, SwedenRecruiting
Kristianstad hospitalKristianstad, SwedenRecruiting
Skåne University Hospital, LundLund, SwedenRecruiting
Skåne University Hospital, MalmöMalmö, SwedenRecruiting
Västmanland hospital VästeråsVästerås, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT05224401