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Study identifier: NCT05221021 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Vaginal Estradiol vs Oral Beta-3 Agonist for Overactive Bladder Syndrome

Condition: Overactive Bladder Syndrome  ·  Sponsor: Walter Reed National Military Medical Center

PhasePhase 4
Planned participants152
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersYes

About this study

A single site, double-blinded, randomized controlled trial for postmenopausal women with urinary frequency, urgency, nocturia with or without urgency urinary incontinence symptoms. Patient's will be randomized between 0.01% vaginal estradiol cream with placebo oral pill or daily 50 milligrams oral Mirabegron with a placebo vaginal cream for 12 weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Christopher W Heuer, DO  ·  2626231053  ·  christopher.w.heuer@gmail.com

Katherine L Dengler, MD  ·  3522626861  ·  katidengler12@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Walter Reed National Military Medical CenterBethesda, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05221021