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Study identifier: NCT05219617 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults

Condition: Seizures · Lennox Gastaut Syndrome  ·  Sponsor: SK Life Science, Inc.

PhasePhase 3
Planned participants252
Who can joinAll sexes, 4 Years to 55 Years
Healthy volunteersNo

About this study

The primary objective is to evaluate the efficacy of carisbamate (YKP509) as adjunctive treatment in reducing the number of drop seizures (tonic, atonic, and tonic-clonic) compared with placebo in pediatric and adult subjects (age 4-55 years) diagnosed with Lennox Gastaut Syndrome (LGS).

This description comes directly from the study's public registry record.

Talk to the study team

Barbara Remes  ·  201-421-3810  ·  bremes@sklsi.com

Always discuss trial participation with your own doctor first.

Locations (71)

Stanford University HospitalPalo Alto, California, United StatesRecruiting
University of Florida Health Science CenterJacksonville, Florida, United StatesCompleted
AdventHealthOrlando, Florida, United StatesCompleted
Pediatric Epilepsy and Neurology SpecialistsTampa, Florida, United StatesRecruiting
University of South FloridaTampa, Florida, United StatesCompleted
Axcess Medical ResearchWellington, Florida, United StatesCompleted
Consultants in Epilepsy and Neurology PLLCBoise, Idaho, United StatesCompleted
Bluegrass Epilepsy Research, LLCLexington, Kentucky, United StatesCompleted
University Medical Center New OrleansNew Orleans, Louisiana, United StatesCompleted
Johns Hopkins HospitalBaltimore, Maryland, United StatesRecruiting
Mid-Atlantic Epilepsy and Sleep CenterBethesda, Maryland, United StatesRecruiting
Mayo ClinicRochester, Minnesota, United StatesCompleted

+ 59 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05219617