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Study identifier: NCT05213806 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

WithHolding Enteral Feeds Around Blood Transfusion (International)

Condition: Necrotizing Enterocolitis  ·  Sponsor: IWK Health Centre

PhaseNA
Planned participants4333
Who can joinAll sexes, N/A to 30 Weeks
Healthy volunteersNo

About this study

The WHEAT International trial is a comparative effectiveness trial exploring whether withholding enteral feeds around the time of blood transfusion in very premature infants (\<30 weeks) will reduce the occurrence of Necrotizing Enterocolitis (NEC). Currently both continued feeding and withholding feeding are approved care practices. The current study will randomize infants from Neonatal Intensive Care Units (NICUs) across Canada and the United Kingdom (UK) into one of the two care approaches (withholding or continued feeds) to determine if any significant outcomes are found.

This description comes directly from the study's public registry record.

Talk to the study team

Cari-Lee Carnell  ·  9024706630  ·  cari-lee.carnell@iwk.nshealth.ca

Tara Hatfield  ·  9024706630  ·  tara.hatfield@iwk.nshealth.ca

Always discuss trial participation with your own doctor first.

Locations (40)

IWK HealthHalifax, Nova Scotia, CanadaRecruiting
Norfolk & Norwich University Hospitals NHS Foundation Trust (Norfolk & Norwich University Hospital)Norwich, England, United KingdomRecruiting
The Hillingdon Hospitals NHS Foundation Trust (Hillingdon Hospital)Hillingdon, UK, United KingdomRecruiting
Barts Health NHS Trust (3 Hospitals: Royal London Hospital, Whipps Cross Hospital, Newham General Hospital)London, UK, United KingdomRecruiting
Chelsea and Westminster Hospital NHS Foundation Trust (Chelsea and Westminster Hospital)London, UK, United KingdomRecruiting
Imperial College Healthcare NHS Trust (2 Hospitals: St Mary's Hospital & Queen Charlotte's and Chelsea Hospital)London, UK, United KingdomRecruiting
Bedfordshire Hospitals NHS Foundation Trust (Luton & Dunstable University Hospital)Luton, UK, United KingdomRecruiting
East Kent University Hospitals NHS Foundation Trust (William Harvey Hospital)Ashford, United KingdomRecruiting
Buckinghamshire Healthcare NHS Trust (Stoke Mandeville Hospital)Aylesbury, United KingdomRecruiting
Barnsley Hospital NHS Foundation TrustBarnsley, United KingdomRecruiting
Birmingham Women's and Children's NHS Foundation Trust (Birmingham Women's Hospital NICU)Birmingham, United KingdomRecruiting
University Hospitals Birmingham NHS Trust (2 Hospitals: Heartland's Hospital & Good Hope Hospital)Birmingham, United KingdomRecruiting

+ 28 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05213806