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Study identifier: NCT05211557 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of Fully Human B7H3 CAR-T in Treating Recurrent Malignant Ovarian Cancer

Condition: Ovarian Cancer  ·  Sponsor: The Affiliated Hospital of Xuzhou Medical University

PhasePhase 1/Phase 2
Planned participants15
Who can joinFemale, 18 Years to 70 Years
Healthy volunteersNo

About this study

This is single center, open-label phase I, non-randomized study which will enroll patients with recurrent advanced ovarian cancer to evaluate the safety, feasibility, and efficacy of fully human B7H3 CAR-T cells (fhB7H3.CAR-Ts) via using a '3+3+3' dose escalation design. In the dose expansion cohort, six patients will be enrolled to further assess their efficacy with the optimal dosage.

This description comes directly from the study's public registry record.

Talk to the study team

Liantao Li, M.D., Ph.D.  ·  +86-516-85582530  ·  liliantao@xzhmu.edu.cn

Xin Ding, M.D., Ph.D.  ·  +86-516-83355832  ·  dingxin81@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

The Affiliated Hospital of Xuzhou Medical UniversityXuzhou, Jiangsu, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05211557