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Study identifier: NCT05208190 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial

Condition: Schizophrenia · Schizoaffective Disorder  ·  Sponsor: New York State Psychiatric Institute

PhasePhase 4
Planned participants280
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Two-hundred and eighty individuals with schizophrenia who have a recent history of violent acts will be randomized in this 2-arm, parallel-group, 24-week, open-label, 7-site clinical trial to examine the effects of treatment with clozapine vs antipsychotic treatment as usual (TAU) for reducing the risk of violent acts in real-world settings

This description comes directly from the study's public registry record.

Talk to the study team

Ragy Girgis  ·  646-774-5553  ·  ragy.girgis@nyspi.columbia.edu

Always discuss trial participation with your own doctor first.

Locations (7)

University of California, Los AngelesLos Angeles, California, United StatesRecruiting
Augusta University Research Institute, Inc.Augusta, Georgia, United StatesRecruiting
University of Maryland School of MedicineBaltimore, Maryland, United StatesRecruiting
NYU Langone Medical CenterNew York, New York, United StatesRecruiting
New York State Psychiatric InstituteNew York, New York, United StatesRecruiting
Manhattan Psychiatric CenterNew York, New York, United StatesRecruiting
University of North Carolina at Chapel HillChapel Hill, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05208190