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Study identifier: NCT05205850 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of RC118 in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Condition: Advanced Solid Tumor  ·  Sponsor: RemeGen Co., Ltd.

PhasePhase 1/Phase 2
Planned participants135
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

In Phase I, This study will explore the tolerability and safety of RC118 in patients with locally advanced unresectable or metastatic malignant solid tumors with positive Claudin 18.2 expression, and determine the maximum tolerated dose (MTD) and the recommended dose in phase II clinical trials (RP2D); In Phase IIa, to explore the clinical effectiveness and safety of long-term use of RC118 at RP2D doses for patients with different tumor types。

This description comes directly from the study's public registry record.

Talk to the study team

Jianming Fang, ph.D  ·  +8610-58075763  ·  jianmingfang@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Zhongshan Hospital Affiliated to Fudan UniversityShanghai, Shanghai Municipality, ChinaRecruiting
The first affiliated hospital, zhejiang universtity school of medicineHangzhou, Zhejiang, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05205850