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Study identifier: NCT05201469 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

VIBRANT: VIB4920 for Active Lupus Nephritis

Condition: Lupus Nephritis  ·  Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

PhasePhase 2
Planned participants74
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in participants with active lupus nephritis (LN).

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (17)

University of California San Diego School of Medicine: Division of Rheumatology, Allergy and ImmunologyLa Jolla, California, United StatesRecruiting
UCLA Medical Center: Division of RheumatologyLos Angeles, California, United StatesRecruiting
of California, Irvine School of Medicine Division of RheumatologyOrange, California, United StatesRecruiting
University of California San Francisco School of Medicine: Lupus Clinic and Rheumatology Clinical Research CenterSan Francisco, California, United StatesRecruiting
University of Colorado School of Medicine: Division of RheumatologyAurora, Colorado, United StatesRecruiting
Yale University School of Medicine: Section of RheumatologyNew Haven, Connecticut, United StatesRecruiting
University of Miami Miller School of Medicine: Nephrology & Hypertension DivisionMiami, Florida, United StatesRecruiting
Emory University School of Medicine: Division of RheumatologyAtlanta, Georgia, United StatesRecruiting
University of Chicago, Department of Medicine: RheumatologyChicago, Illinois, United StatesRecruiting
University of MichiganAnn Arbor, Michigan, United StatesRecruiting
Washington University School of Medicine in St. Louis: Division of NephrologySt Louis, Missouri, United StatesRecruiting
Feinstein Institute for Medical Research: Center for Autoimmune and Musculoskeletal DiseasesManhasset, New York, United StatesRecruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05201469