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Study identifier: NCT05197881 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Daily Adaptive Radiation Therapy an Individualized Approach for Carcinoma of the Cervix

Condition: Cervical Cancer by FIGO Stage 2018  ·  Sponsor: Varian, a Siemens Healthineers Company

PhaseNA
Planned participants125
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a single-arm, prospective, multi-center clinical trial designed to demonstrate that adaptive radiotherapy for locally advanced cervical cancer will translate into a decreased rate of acute gastrointestinal toxicity compared with the historically reported rate for non-adaptive intensity modulated radiation therapy (IMRT). The timepoint for this assessment will be at week 5 of external beam radiotherapy (EBRT) and will use the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE).

This description comes directly from the study's public registry record.

Talk to the study team

Heike Hausen, MD  ·  1-650-743-7400  ·  heike.hausen@varian.com

Sean Davidson, MS  ·  sean.davidson@varian.com

Always discuss trial participation with your own doctor first.

Locations (5)

University of Alabama BirminghamBurmingham, Alabama, United StatesRecruiting
University of Arkansas Medical SciencesLittle Rock, Arkansas, United StatesRecruiting
Moores Cancer Center at UC San Diego HealthLa Jolla, California, United StatesRecruiting
Fox Chase Cancer CenterPhiladelphia, Pennsylvania, United StatesRecruiting
University of Texas SouthwesternDallas, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05197881