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Study identifier: NCT05196503 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy of an Intraoperative Periradicular Application of Platelet Rich Fibrin (PRF) on the Intensity of Residual Post-surgical Neuropathic Pain After a Surgery for Disc Herniation

Condition: Neuropathic Pain · Chronic Postsurgical Pain  ·  Sponsor: University Hospital, Strasbourg, France

PhasePhase 3
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The prevalence of post-surgical lumbar neuropathic radiculopathy is approximately 30%. Poor response to the treatments recommended for neuropathic pain, namely antidepressants and/or gabapentinoids, requires the development of new techniques to prevent this chronic pain. Certain well-tolerated techniques, such as the administration of plasma enriched with platelets and fibrin (PRF), are increasingly used in regenerative medicine for their anti-inflammatory and analgesic properties. Thus, a periradicular intraoperative application of PRF may have an analgesic effect on the intensity of residual postsurgical neuropathic pain after disc herniation surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Erci SALVAT  ·  +33 3 88 12 85 02  ·  eric.salvat@chru-strasbourg.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Les Hôpitaux UniversitairesStrasbourg, Bas-Rhin, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05196503